EXPEDITIOUS ENANTIOSELECTIVE SYNTHESIS OF CARBOCYCLIC NUCLEOSIDES WITH ANTILEISHMANIAL ACTIVITY

被引：26

作者：

DASILVA, AD

COIMBRA, ES

FOURREY, JL

MACHADO, AS

ROBERTGERO, M

机构：

[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE

[2] UNIV FED MINAS GERAIS,DEPT QUIM,BR-31270 BELO HORIZON,MG,BRAZIL

[3] UNIV FED JUIZ FORA,DEPT QUIM,BR-36100 JUIZ DE FORA,MG,BRAZIL

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 42期

关键词：

NUCLEOSIDE; CARBOCYCLE; PALLADIUM; ANTIBIOTICS;

D O I：

10.1016/S0040-4039(00)61691-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short synthesis of the neplanocin A analogue 1, lacking the hydroxymethylene at C-4 of the parent naturally occurring carbocyclic nucleoside, is described. Moreover, the non toxic noraristeromycin 3, an intermediate in the synthetic scheme, was shown to exhibit a promising anti-leishmanial activity.

引用

页码：6745 / 6748

页数：4

共 13 条

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