DISTURBANCE OF MEAL PATTERNING FOLLOWING NUCLEUS-ACCUMBENS LESIONS IN THE RAT

被引：8

作者：

CLIFTON, PG

SOMERVILLE, EM

机构：

[1] Experimental Psychology, School of Biology, University of Sussex, Brighton

来源：

BRAIN RESEARCH | 1994年 / 667卷 / 01期

关键词：

FEEDING; NUCLEUS ACCUMBENS; YM-09151-2; MEAL PATTERNING; REWARD; SWITCHING;

D O I：

10.1016/0006-8993(94)91722-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In this study, we examined the effects of electrolytic lesions of the nucleus accumbens which had no obvious effect on body weight, or on the short term intake of solid food, sucrose and salt solutions. However in 24-h records of feeding and drinking lesioned animals took many more meals of shorter duration. Challenge with the dopamine D-2 antagonist YM-09151-2 resulted in a decrease in feeding rate, together with a facilitation of meal size in drinking, in both control and lesioned subjects.

引用

页码：123 / 128

页数：6

共 29 条

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[2]

BAKSHI VP, 1991, PSYCHOBIOLOGY, V19, P223

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