A NEW MECHANISM INVOLVING CYCLIC TAUTOMERS FOR THE REACTION WITH NUCLEOPHILES OF THE WATER-SOLUBLE PEPTIDE COUPLING REAGENT 1-ETHYL-3-(3-(DIMETHYLAMINO)PROPYL)CARBODIIMIDE (EDC)

被引：83

作者：

WILLIAMS, A

IBRAHIM, IT

机构：

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1981年 / 103卷 / 24期

关键词：

D O I：

10.1021/ja00414a011

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：7090 / 7095

页数：6

共 24 条

[1]

Carraway K L, 1972, Methods Enzymol, V25, P616, DOI 10.1016/S0076-6879(72)25060-1

[2] APPLICATION OF HAMMETT EQUATION TO AMIDINES [J].

CHARTON, M .

JOURNAL OF ORGANIC CHEMISTRY, 1965, 30 (04) :969-&

[3] DEFINITION OF INDUCTIVE SUBSTITUENT CONSTANTS [J].

CHARTON, M .

JOURNAL OF ORGANIC CHEMISTRY, 1964, 29 (05) :1222-&

[4] GENERAL BASE CATALYZED HYDROLYSIS OF N,N'-DIMETHYL-N,N'-DIPHENYLAMIDINIUM SALTS [J].

DEWOLFE, RH ;

CHENG, MWL .

JOURNAL OF ORGANIC CHEMISTRY, 1969, 34 (09) :2595-&

[5] KINETICS OF HYDROLYSIS OF N,N]-DIARYLFORMAMIDINES IN ALKALINE DIOXANE SOLUTIONS [J].

DEWOLFE, RH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (05) :864-&

[6]

Hansson J., 1955, SVENSK KEM TIDSKR, V67, P256

[7]

HUNIG S, 1953, LIEBIGS ANN CHEM, V579, P77

[8]

IBRAHIM IB, UNPUBLISHED

[9] CONCERTED GENERAL ACID CATALYSIS IN THE REACTION OF ACETATE ION WITH WATER-SOLUBLE CARBODI-IMIDE [J].

IBRAHIM, IT ;

WILLIAMS, A .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1980, (01) :25-27

[10] REACTION OF WATER-SOLUBLE REAGENT N-ETHYL-N'-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE WITH NUCLEOPHILES - PARTICIPATION OF TAUTOMERIC CYCLIC AMMONIOAMIDINE AS A KINETICALLY IMPORTANT INTERMEDIATE [J].

IBRAHIM, IT ;

WILLIAMS, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (23) :7420-7421

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