ORGANOMETALLIC COMPOUNDS .63. SYNTHESIS, OPTICAL STABILITY, STEREO-SELECTIVE AND STEREO-SPECIFIC REACTIONS OF CHIRAL TRIORGANOTIN HYDRIDES

Optically active triorganotin hydrides have been synthesized by asymmetric reduction of the corresponding halides. These optically stable compounds undergo stereoselective conversions into other optically stable compounds such as tetraorganotin compounds (by reaction with diazomethane or with bifluorenylidene) or hexaorganoditin compounds (by reaction in the presence of palladium) or into optically unstable compounds such as methylneophylphenyltin chloride (by reaction with CCl4). The HD exchange between optically active methylneophylphenyltin hydride (deuteride) and triphenyltin deuteride (hydride) occurs with retention of configuration at the metal atom. © 1979.