SURGICAL PALLIATION FOR PANCREATIC-CANCER - THE UCLA EXPERIENCE

被引:191
作者
SINGH, SM
LONGMIRE, WP
REBER, HA
机构
[1] UNIV CALIF LOS ANGELES,MED CTR,SCH MED,DEPT SURG,ROOM 72-215 CHS,10833 LE CONTE AVE,LOS ANGELES,CA 90024
[2] VET ADM MED CTR,SURG SERV,SEPULVEDA,CA 91343
关键词
D O I
10.1097/00000658-199008000-00003
中图分类号
R61 [外科手术学];
学科分类号
摘要
We reviewed the records of 340 patients with a tissue diagnosis of pancreatic cancer treated at UCLA Medical Center between 1973 and 1988. Sixty-one patients underwent pancreatic resection (group I), 173 had some form of surgical palliation (group II), and 106 had neither (group III). The diagnosis was made 1 to 2 months more quickly in the last 8 years of the review than in the first 8 years, but the effect of early diagnosis on curability was negligible. Biliary obstruction was best treated by cholecystojejunostomy or choledochojejunostomy, which were equally effective. Anastomoses to the jejunum were safer and more effective than were those to the duodenum for the relief of biliary obstruction. Gastrojejunostomy should be performed prophylactically as well as therapeutically. It was effective and safe in both settings. Surgical palliation for pancreatic cancer was generally effective and was associated with an operative mortality rate of less than 10%. However morbidity was high, with significant complications occurring in one third of cases.
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页码:132 / 139
页数:8
相关论文
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