CAPILLARY ZONE ELECTROPHORESIS OF PATHOLOGICAL METABOLITES IN PHENYLKETONURIA

被引:12
作者
DOLNIK, V
机构
[1] Institute of Analytical Chemistry, Academy of Sciences of the Czech Republic, Brno, CZ-611 42
关键词
PHENYLKETONURIA; PHENYLPYRUVATE; PHENYLACETATE; 2-HYDROXYPHENYLACETATE; PHENYLLACTATE; CAPILLARY ZONE ELECTROPHORESIS;
D O I
10.1002/mcs.1220060112
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The pathological metabolites (phenylpyruvate, 2-hydroxyphenylacetate, phenyllactate, and phenylacetate) from urine of phenyllketonuric individuals were separated by capillary zone electrophoresis within 12 minutes. Significant differences in the content of these metabolites in urine can be found ifa healthy man, a phenylketonuric newborn, and a phenylketonuric individual on a low-phenylalanine diet are compared.
引用
收藏
页码:63 / 67
页数:5
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