STEROIDS .6. ACID-CATALYSED WITTIG REACTION

被引：18

作者：

BOSE, AK

MANHAS, MS

RAMER, RM

机构：

[1] Department of Chemistry and Chemical Engineering, Stevens Institute of Technology, Hoboken

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 19期

关键词：

D O I：

10.1039/j39690002728

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Wittig reaction between resonance-stabilised phosphoranes and steroid ketones under acid catalysis has been studied. Only ethoxycarbonylmethylene- and cyanomethylene-triphenylphosphorane and 3-oxo-steroids having no α-substituents can be successfully employed in this reaction. The stereochemistry of the olefin produced is the same as in the corresponding Wittig reaction conducted under basic conditions.

引用

页码：2728 / &

共 8 条

[1]

BOSE AK, 1966, TETRAHEDRON LETT, P6263

[2] STEROIDS .3. TRANSFORMATIONS OF STEROID KETONES USING PHOSPHONATE CARBANIONS [J].