EFFECTS OF ESTRADIOL-17-BETA ON REPRODUCTION IN ADULT MALE-RATS

被引：16

作者：

HUNT, DM ^{[1
]}

SAKSENA, SK ^{[1
]}

CHANG, MC ^{[1
]}

机构：

[1] WORCESTER FDN EXPTL BIOL,SHREWSBURY,MA 01545

来源：

ARCHIVES OF ANDROLOGY | 1979年 / 2卷 / 02期

关键词：

Estradiol-17β; Fertility; LH; Male Rat; Steroids;

D O I：

10.3109/01485017908987304

中图分类号：

R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

摘要：

Estradiol-17/3 (E2-17β) treatment induced dose-related reduction of sperm population and eventual azoospermia, atrophy of accessory organs, and suppressed serum LH and testosterone levels. In spite of all these alterations mating behavior was not affected, although the number of implantation sites paralleled the reduction of sperm population, suggesting that the primary detectable response to E2-17β treatment is related to the steroidogenic components of the testis and the hypothalamic pituitary axis. The duration of treatment is more critical for the induction of azoospermia in the rat than the total dose of E2-17β. © 1979 Informa UK Ltd.

引用

页码：129 / 133

页数：5

共 15 条

[1] EFFECTS OF ESTROGENS ON TESTICULAR TESTOSTERONE PRODUCTION INVITRO [J].