EFFECT OF BRIGHT LIGHT IN THE MORNING ON DIURNAL-VARIATIONS OF PINEAL INDOLES IN NZBWF1 MICE

被引：2

作者：

AZUMA, H ^{[1
]}

YAMATODANI, A ^{[1
]}

YAGI, A ^{[1
]}

NISHIMURA, T ^{[1
]}

WADA, H ^{[1
]}

机构：

[1] OSAKA UNIV,FAC MED,DEPT PHARMACOL 2,OSAKA 553,JAPAN

来源：

NEUROSCIENCE LETTERS | 1991年 / 131卷 / 02期

关键词：

CIRCADIAN RHYTHM; PINEAL; INDOLE; BRIGHT LIGHT; NZBWF1; MOUSE; SEASONAL AFFECTIVE DISORDER;

D O I：

10.1016/0304-3940(91)90615-Z

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Exposure to bright light (2000 1x) for 2 h at the beginning of a 12 h light period (10 1x) resulted in about 1 h advances in the onset and termination of N-acetylserotonin (NAc5HT) synthesis in the pineal gland of NZBWF1 strain mice compared with those in mice not exposed to bright light. These effects are in contrast with the effect of exposure to bright light throughout the light period, which delayed the onset of pineal NAc5HT synthesis in NZB mice. The possible relationship of these effects with the mechanism of action of phototherapy of human affective disorder is discussed.

引用

页码：210 / 212

页数：3

共 10 条

[1] INFLUENCE OF INTENSITY OF ILLUMINATION DURING THE LIGHT PERIOD ON DIURNAL-VARIATIONS OF PINEAL INDOLES IN RATS AND MICE [J].