PHOTOREVERSIBLE ANTIGEN-ANTIBODY REACTIONS

被引：31

作者：

HARADA, M

SISIDO, M

HIROSE, J

NAKANISHI, M

机构：

[1] TOKYO INST TECHNOL,GRAD SCH NAGATSUTA,RESOURCES UTILIZAT RES LAB,4259 NAGATSUTA,MIDORI KU,YOKOHAMA,KANAGAWA 227,JAPAN

[2] NAGOYA CITY UNIV,FAC PHARMACEUT SCI,MIZUHO KU,NAGOYA,AICHI 467,JAPAN

来源：

FEBS LETTERS | 1991年 / 286卷 / 1-2期

关键词：

MONOCLONAL ANTIBODY; PHOTOCHROMIC HAPTEN; AZOBENZENE; PHOTOCONTROL;

D O I：

10.1016/0014-5793(91)80928-V

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A monoclonal antibody (Z1H01) for an oligopeptide carrying an azobenzene group, was prepared under conditions where the azobenzene group is in the trans form. The antibody bound the hapten peptide effectively when the hapten peptide is in the trans form (K = 5 x 10(7) M-1), but the antibody released the hapten under irradiation with UV light where the hapten is in the cis form. The antibody bound the hapten again, when the hapten reverted to the trans form after irradiation with visible light.

引用

页码：6 / 8

页数：3

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