INVITRO SUSCEPTIBILITY OF YEAST ISOLATES FROM THE BLOOD TO FLUCONAZOLE AND AMPHOTERICIN-B

被引：23

作者：

DERMOUMI, H

机构：

[1] Institute of Medical Microbiology, University of Essen

来源：

CHEMOTHERAPY | 1992年 / 38卷 / 02期

关键词：

BLOOD CULTURES; INVITRO SUSCEPTIBILITY; INHIBITORY CONCENTRATION; FLUCONAZOLE; AMPHOTERICIN-B; YEASTS;

D O I：

10.1159/000238950

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

221 yeast strains including 131 of Candida albicans, 21 of C. tropicalis, 23 of C. parapsilosis, 19 of C. glabrata, 7 of C guilliermondii, 6 of C. krusei and of other species were isolated from the blood. The activity of fluconazole and amphotericin B was investigated by means of a photometer-read broth microdilution method measuring the 30% inhibitory concentrations (IC30). The results of fluconazole showed a higher susceptibility of C. albicans compared to the other species. However, 6 (4.5%) resistant strains of C. albicans were found. Low sensitivity and resistance were evaluated for C. krusei and C. glabrata strains. All isolates showed susceptibility to amphotericin B.

引用

页码：112 / 117

页数：6

共 25 条

[1]

[Anonymous], 1985, MANUAL CLIN MICROBIO

[2]

DERMOUMI H, 1987, MYCOSES, V30, P349, DOI 10.1111/j.1439-0507.1987.tb03627.x

[3]

DROUHET E, 1986, P31

[4]

FOX R, 1991, J INFECTION, V22, P211