ARE THE PRE-SYNAPTIC MEMBRANE-PARTICLES THE CALCIUM CHANNELS

被引：303

作者：

PUMPLIN, DW

REESE, TS

LLINAS, R

机构：

[1] UNIV MARYLAND, SCH MED, DEPT ANAT, BALTIMORE, MD 21201 USA

[2] NIH, FUNCT NEUROANAT SECT, BETHESDA, MD 20205 USA

[3] NYU MED CTR, DEPT PHYSIOL & BIOPHYS, NEW YORK, NY 10016 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES | 1981年 / 78卷 / 11期

关键词：

D O I：

10.1073/pnas.78.11.7210

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The number of large intramembrane particles associated with sites of synaptic vesicle release at the squid giant synapse was determined and compared to the average maximal presynaptic Ca current to derive an estimate of the conductance each particle would have if it were a Ca channel. This value, 0.21 pS, compares favorably with conductances of Ca channels in other preparations, substantiating the idea that the large intramembrane particles, which are concentrated at active zones, represent Ca channels.

引用

页码：7210 / 7213

页数：4

共 25 条

[1] UNITS OF CALCIUM CONDUCTION IN HELIX NEURONS [J].