ELECTRICAL-STIMULATION OF THE VAGUS INCREASES EXTRACELLULAR GLUTAMATE RECOVERED FROM THE NUCLEUS-TRACTUS-SOLITARII OF THE CAT BY IN-VIVO MICRODIALYSIS

被引：61

作者：

ALLCHIN, RE ^{[1
]}

BATTEN, TFC ^{[1
]}

MCWILLIAM, PN ^{[1
]}

VAUGHAN, PFT ^{[1
]}

机构：

[1] UNIV LEEDS,RES SCH MED,LEEDS LS2 9JT,W YORKSHIRE,ENGLAND

来源：

EXPERIMENTAL PHYSIOLOGY | 1994年 / 79卷 / 02期

关键词：

D O I：

10.1113/expphysiol.1994.sp003761

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Release of glutamate into the extracellular space of the cat nucleus tractus solitarii (NTS) was measured by in vivo microdialysis and high performance liquid chromatography. Perfusion of the probe with 100 mm potassium increased glutamate release by 21 1 % (P < 0.00 1), while electrical stimulation of the cervical vagus increased release by 53 % (P < 0.01). These results are compatible with the hypothesis that glutamate is a neurotransmitter released by vagal afferent nerve terminals in the NTS.

引用

页码：265 / 268

页数：4

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