HYDROGENATION OF 1-BENZYL-3-(2,2-DIMETHYL-1,3-DIOXOLAN-4-YL)-AZIRIDINE-2-CARBOXYLIC ACID ETHYL-ESTER

被引：6

作者：

AMBROSI, HD

DUCZEK, W

RAMM, M

JAHNISCH, K

机构：

[1] INST ANGEW CHEM,D-12484 BERLIN,GERMANY

[2] TECH FACHHSCH BERLIN,D-13353 BERLIN,GERMANY

[3] FREE UNIV BERLIN,INST KRISTALLOG,D-14195 BERLIN,GERMANY

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(00)78356-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hydrogenation of 1-benzyl-aziridine-2-carboxylic acid ethyl ester 1 yielded the enantiomerically pure 1H-aziridine 2 or the beta-amino acid ester 3 as main products depending on the reaction time. The Z-protected derivatives of 2 and 3 were transformed into the gamma-lactones 4 and 5, respectively.

引用

页码：7613 / 7616

页数：4

共 7 条

[1]

AMBROSI HD, 1994, IN PRESS LIEBIGS ANN

[2] AMINO-ACID SYNTHESIS VIA RING-OPENING OF N-SULFONYL AZIRIDINE-2-CARBOXYLATE ESTERS WITH ORGANOMETALLIC REAGENTS [J].