A STUDY OF BIRTH-ORDER AND MULTIPLE-SCLEROSIS IN MULTIPLEX FAMILIES

被引：14

作者：

GAUDET, JPC

HASHIMOTO, L

SADOVNICK, AD

EBERS, GC

机构：

[1] UNIV WESTERN ONTARIO HOSP,MULTIPLE SCLEROSIS CLIN,LONDON,ON N6A 5A5,CANADA

[2] UNIV WESTERN ONTARIO HOSP,DEPT CLIN NEUROL SCI,LONDON,ON N6A 5A5,CANADA

[3] VANCOUVER HOSP & HLTH SCI CTR,MULTIPLE SCLEROSIS CLIN,VANCOUVER,BC,CANADA

[4] UNIV BRITISH COLUMBIA,DEPT MED GENET,VANCOUVER,BC,CANADA

来源：

NEUROEPIDEMIOLOGY | 1995年 / 14卷 / 04期

关键词：

MULTIPLE SCLEROSIS; BIRTH ORDER; MULTIPLEX FAMILIES;

D O I：

10.1159/000109795

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Birth order position for affected siblings was examined for ss sibships having 2 or more cases of multiple sclerosis (MS). The data show that MS patients are randomly ordered by birth within these multiplex sibships. The data therefore do not support the hypothesis that MS occurs in siblings because of a common environmental exposure as defined by proximity in birth order position.

引用

页码：188 / 192

页数：5

共 21 条

[1]

ALPEROVITCH A, 1981, ACTA NEUROL SCAND, V63, P136

[2]

BERGLIN CG, 1992, J EPIDEMIOL COMMUNIT, V36, P298

[3] AGE OF ONSET IN SIBLINGS CONCORDANT FOR MULTIPLE-SCLEROSIS [J].