SEARCHING FOR PHARMACOPHORES IN LARGE COORDINATE DATA-BASES AND ITS USE IN DRUG DESIGN

被引：48

作者：

SHERIDAN, RP

RUSINKO, A

NILAKANTAN, R

VENKATARAGHAVAN, R

机构：

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1989年 / 86卷 / 20期

关键词：

D O I：

10.1073/pnas.86.20.8165

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：8165 / 8169

页数：5

共 19 条

[1] CAMBRIDGE CRYSTALLOGRAPHIC DATA CENTER - COMPUTER-BASED SEARCH, RETRIEVAL, ANALYSIS AND DISPLAY OF INFORMATION [J].

ALLEN, FH ;

BELLARD, S ;

BRICE, MD ;

CARTWRIGHT, BA ;

DOUBLEDAY, A ;

HIGGS, H ;

HUMMELINK, T ;

HUMMELINKPETERS, BG ;

KENNARD, O ;

MOTHERWELL, WDS ;

RODGERS, JR ;

WATSON, DG .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1979, 35 (OCT) :2331-2339

[2] PROTEIN DATA BANK - COMPUTER-BASED ARCHIVAL FILE FOR MACROMOLECULAR STRUCTURES [J].

BERNSTEIN, FC ;

KOETZLE, TF ;

WILLIAMS, GJB ;

MEYER, EF ;

BRICE, MD ;

RODGERS, JR ;

KENNARD, O ;

SHIMANOUCHI, T ;

TASUMI, M .

JOURNAL OF MOLECULAR BIOLOGY, 1977, 112 (03) :535-542

[3]

CHEUNG HS, 1980, J BIOL CHEM, V255, P401

[4]

CORDELL GA, 1981, INTRO ALKALOIDS BIOG, P554

[5] DISTANCE GEOMETRY APPROACH TO RATIONALIZING BINDING DATA [J].

CRIPPEN, GM .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (08) :988-997

[6]

GUND P, 1977, PROGR MOL SUBCELLULA, V5, P1117

[7]

GUND P, 1974, P INT C COMPUTERS CH, V3, P33

[8] THE DESIGN OF A NEW GROUP OF ANGIOTENSIN-CONVERTING ENZYME-INHIBITORS [J].

HASSALL, CH ;

KROHN, A ;

MOODY, CJ ;

THOMAS, WA .

FEBS LETTERS, 1982, 147 (02) :175-179

[9]

JAKES SE, 1987, J MOL GRAPHICS, V5, P41

[10] A COMMON STRUCTURAL MODEL FOR CENTRAL-NERVOUS-SYSTEM DRUGS AND THEIR RECEPTORS [J].

LLOYD, EJ ;

ANDREWS, PR .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (04) :453-462

← 1 2 →