DETECTION OF BM86 ANTIGEN IN DIFFERENT STRAINS OF BOOPHILUS-MICROPLUS AND EFFECTIVENESS OF IMMUNIZATION WITH RECOMBINANT BM86

被引：30

作者：

PENICHET, M

RODRIGUEZ, M

CASTELLANO, O

MANDADO, S

ROJAS, Y

RUBIERA, R

SANCHEZ, P

LLEONART, R

DELAFUENTE, J

机构：

[1] CTR INGN GENET & BIOTECNOL,DIV MAMMALIAN CELL GENET,HAVANA,CUBA

[2] CTR INT RESTAURAC NEUROL,HAVANA,CUBA

[3] INST GASTROENTEROL,HAVANA,CUBA

[4] ESTAC EXPTL PARASITOL,HAVANA,CUBA

来源：

PARASITE IMMUNOLOGY | 1994年 / 16卷 / 09期

关键词：

BOOPHILUS MICROPLUS; TICK; ANTIGEN; BM86; IMMUNOHISTOCHEMISTRY;

D O I：

10.1111/j.1365-3024.1994.tb00377.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The control of tick populations by using conventional strategies poses several problems, including the appearance of organophosphate resistant strains, among others. The possibility of using alternative strategies such as vaccination with tick antigens has been suggested by several authors. One particular antigen (Bm86) has been described and shown to be able to induce a protective immunity against the cattle tick Boophilus microplus. In this paper we demonstrate by means of immunohistochemical staining that this antigen is conserved among several strains of this species. These results correlate with those showing that animals vaccinated with a preparation of recombinant Bm86 were protected against challenge with the four different strains tested including one resistant to organophosphates. These results favour the immunization with recombinant Bm86 for the control of the cattle rick B. microplus.

引用

页码：493 / 500

页数：8

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