GENERAL-SYNTHESIS OF 2'-HYDROXYCHALCONES FROM BROMOMAGNESIUM PHENOXIDES AND CINNAMIC ALDEHYDES

被引：14

作者：

CASIRAGHI, G ^{[1
]}

CASNATI, G ^{[1
]}

DRADI, E ^{[1
]}

MESSORI, R ^{[1
]}

SARTORI, G ^{[1
]}

机构：

[1] UNIV PARMA,IST CHIM ORGAN,I-43100 PARMA,ITALY

来源：

TETRAHEDRON | 1979年 / 35卷 / 17期

关键词：

D O I：

10.1016/S0040-4020(01)88979-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly selective synthetic route of general utility was devised for the preparation of 2'-hydroxychalcones 4. The procedure involves the regiochemical controlled reaction between bromomagnesium salts of mono and dihydric phenols 1 and variously substituted cinnamaldehydes 2 in aprotic apolar media and in the presence of a suitable basic additive. Application of this procedure to some naturally occurring chalcones is reported. The crucial role of the additive is also emphasized. © 1979.

引用

页码：2061 / 2065

页数：5

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