ALKYLATION OF KETONES BY USE OF SOLID KOH IN DIMETHYL-SULFOXIDE

被引：36

作者：

LANGHALS, E

LANGHALS, H

机构：

[1] CONSORTIUM ELEKTROCHEM IND,ZIELSTATTSTR 20,W-8000 MUNICH 70,GERMANY

[2] UNIV MUNICH,INST ORGAN CHEM,W-8000 MUNICH 2,GERMANY

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(00)94647-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A mixture of solid KOH in dimethyl sulfoxide has a strong basicity, but only a low nucleophilicity and is used for methylation of ketones. With this simple and inexpensive reagent complete methylation with yields up to 90% can be achieved. © 1990.

引用

页码：859 / 862

页数：4

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