SYNTHETIC APPLICATIONS OF N-N LINKED HETEROCYCLES .6. REGIOSPECIFIC NUCLEOPHILIC-ATTACK AT THE GAMMA-POSITION OF 1-(2,6-DIMETHYL-4-OXO-1,4-DIHYDRO-1-PYRIDYL)PYRIDINIUM COMPOUNDS - NOVEL SYNTHESIS OF 4-SUBSTITUTED PYRIDINES

被引：38

作者：

KATRITZKY, AR ^{[1
]}

BELTRAMI, H ^{[1
]}

KEAY, JG ^{[1
]}

ROGERS, DN ^{[1
]}

SAMMES, MP ^{[1
]}

LEUNG, CWF ^{[1
]}

LEE, CM ^{[1
]}

机构：

[1] UNIV HONG KONG,DEPT CHEM,HONG KONG,HONG KONG

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1979年 / 18卷 / 10期

关键词：

D O I：

10.1002/anie.197907922

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Syntheses of 4‐substituted pyridines 3 are always of interest. In the pyridinium ion 1 positions 2 and 6 are sterically shielded; it therefore reacts at the activated position 4 with C, N and S nuleophiles in high yields to give 2, which is readily cleaved to 3 and 4, or decomposes to these products. (Figure Presented.) Copyright © 1979 by Verlag Chemie, GmbH, Germany

引用

页码：792 / 793

页数：2

共 14 条

[1]

Arens JF, 1942, RECL TRAV CHIM PAY-B, V61, P59

[2] ALKYL NITRATE NITRATION OF ACTIVE METHYLENE COMPOUNDS .9. NITRATION OF ALKYL SUBSTITUTED HETEROCYCLIC-COMPOUNDS [J].