INCREASED RISK OF CANCER IN PATIENTS WITH SYSTEMIC LUPUS-ERYTHEMATOSUS

被引：159

作者：

PETTERSSON, T

PUKKALA, E

TEPPO, L

FRIMAN, C

机构：

[1] UNIV HELSINKI,CENT HOSP,DEPT MED 4,UNIONINKATU 38,SF-00170 HELSINKI 17,FINLAND

[2] FINNISH CANC REGISTRY,HELSINKI,FINLAND

来源：

ANNALS OF THE RHEUMATIC DISEASES | 1992年 / 51卷 / 04期

关键词：

D O I：

10.1136/ard.51.4.437

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To evaluate the risk of cancer in patients with systemic lupus erythematosus (SLE) a series of 205 consecutive patients (182 women and 23 men) were followed up for cancer through the files of the Finnish Cancer Registry. The follow up consisted of a total of 2340 person years. Fifteen cancers were diagnosed against 5.7 expected (relative risk (RR) 2.6, 95% confidence interval (CI) 1.5 to 4.4). Among the women there were four non-Hodgkin's lymphomas against 0.09 expected (RR 44, CI 11.9 to 111) and two soft tissue sarcomas against 0.04 expected (RR 49, CI 6.0 to 177). When evaluated by a case control study previous treatment with cytostatic drugs showed no influence on the occurrence of cancer in this series of patients with SLE.

引用

页码：437 / 439

页数：3

共 17 条

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