POLYMERIC PHOSPHONIUM SALTS AS A NOVEL CLASS OF CATIONIC BIOCIDES .9. EFFECT OF SIDE-CHAIN LENGTH BETWEEN MAIN-CHAIN AND ACTIVE GROUP ON ANTIBACTERIAL ACTIVITY

被引：36

作者：

KANAZAWA, A ^{[1
]}

IKEDA, T ^{[1
]}

ENDO, T ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,RESOURCES UTILIZAT RES LAB,4259 NAGATSUTA,MIDORI KU,YOKOHAMA,KANAGAWA 227,JAPAN

来源：

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY | 1994年 / 32卷 / 10期

关键词：

POLYMERS WITH PENDANT PHOSPHONIUM SALTS; ANTIBACTERIAL ACTIVITY; EFFECT OF SIDE-CHAIN LENGTH; VIABLE CELL COUNTING METHOD; POLYCATIONIC BIOCIDES;

D O I：

10.1002/pola.1994.080321024

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Polymeric phosphonium salts with different side-chain length between the main chain and the active group, poly[4-(2-tributyl-phosphonioethyl)styrene chloride-co-4-(2-chloroethyl)styrene] and poly[4-(3-tributylphosphoniopropyl)styrene chloride-co-4-(3-chloropropyl)styrene], were prepared and their antibacterial activities against Staphylococcus aureus and Escherichia coli were examined by the viable cell counting method in sterile distilled water. The antibacterial activity was found to decrease as the side-chain length increased. The most significant finding is a peculiar concentration dependence of the antibacterial activity, which demonstrated the presence of an optimal concentration. The observed specific effects of the side-chain length and the concentration on the antibacterial activity seem to be ascribed to the state of aggregation of the polycationic biocides in aqueous solution. (C) 1994 John Wiley & Sons, Inc.

引用

页码：1997 / 2001

页数：5

共 12 条

[1]

BOINON B, 1989, MAKROMOL CHEM, V190, P241

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