ISOLATION AND STRUCTURE ELUCIDATION OF VIRIDIOFUNGIN-A, VIRIDIOFUNGIN-B AND VIRIDIOFUNGIN-C

被引：44

作者：

HARRIS, GH

JONES, ETT

MEINZ, MS

NALLINOMSTEAD, M

HELMS, GL

BILLS, GF

ZINK, D

WILSON, KE

机构：

[1] Merck Research Laboratories, Rahway, NJ 07065

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 33期

关键词：

D O I：

10.1016/S0040-4039(00)73961-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The isolation and structure elucidation of three members of a novel family of amino acid containing alkyl citrates, viridiofungins A (1), B (2) and C (3), are described. They are potent, broad spectrum antifungal agents and in vitro inhibitors of squalene synthase.

引用

页码：5235 / 5238

页数：4

共 5 条

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