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INACTIVATION AND MUTAGENESIS ON ISOLATED DNA .2. KINETICS OF MUTAGENESIS AND EFFICIENCY OF DIFFERENT MUTAGENS

被引：19
作者：
BRESLER, SE
KALININ, VL
PERUMOV, DA
机构：
[1] Institute of High Molecular Weight Compounds, Academy of Sciences, U.S.S.R., Leningrad
来源：
MUTATION RESEARCH | 1968年 / 5卷 / 01期
关键词：
D O I：
10.1016/0027-5107(68)90075-4
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
1. (1) Theoretical concepts are developed on the kinetics of mutagenesis on isolated transforming DNA in vitro. Experimental results are found to be in good agreement with theoretical predictions. 2. (2) The efficiency of different mutagens is characterized on the basis of the developed theory. All investigated agents can be arranged in the following order according to their mutagenic efficiency: NH2OH > HNO2 > N2H4 > dimethylsulfate > UV irradiation > pH 4.2. © 1968.
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