PHYSIOLOGICAL-ROLE FOR CALCITONIN - PROTECTION OF THE MATERNAL SKELETON

被引：191

作者：

STEVENSON, JC ^{[1
]}

HILLYARD, CJ ^{[1
]}

MACINTYRE, I ^{[1
]}

COOPER, H ^{[1
]}

WHITEHEAD, MI ^{[1
]}

机构：

[1] UNIV LONDON KINGS COLL HOSP,SCH MED,DEPT OBSTET,LONDON SE5 8RX,ENGLAND

来源：

LANCET | 1979年 / 2卷 / 8146期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S0140-6736(79)92117-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Plasma-calcitonin levels, measured with an established and reliable extraction radioimmunoassay technique, were significantly higher throughout normal pregnancy and lactation than in normal non-pregnant women, and were not immediately influenced by the acute stimulation of breast-feeding. Thus, more calcitonin circulates at times of physiologically increased calcium need. It is suggested that an important function of calcitonin is the protection of the healthy maternal skeleton from excessive resorption by opposing the resorptive action of 1,25-dihydroxycholecalciferol on bone. © 1979.

引用

页码：769 / 770

页数：2

共 13 条

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