RETRO-BINDING TRIPEPTIDE THROMBIN ACTIVE-SITE INHIBITORS - DISCOVERY, SYNTHESIS, AND MOLECULAR MODELING

被引：26

作者：

IWANOWICZ, EJ

LAU, WF

LIN, J

ROBERTS, DGM

SELLERS, SM

机构：

[1] BRISTOL MYERS SQUIBB PHARMACEUT RES INST, COMP ASSISTED DRUG DESIGN MACROMOLEC STRUCT, PRINCETON, NJ 08543 USA

[2] BRISTOL MYERS SQUIBB PHARMACEUT RES INST, DEPT CARDIOVASC BIOCHEM, PRINCETON, NJ 08543 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1994年 / 37卷 / 14期

关键词：

D O I：

10.1021/jm00040a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：2122 / 2124

页数：3

共 27 条

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[9] DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF A UNIQUE CLASS OF ELASTASE INHIBITORS, THE PEPTIDYL ALPHA-KETOBENZOXAZOLES, AND THE X-RAY CRYSTAL-STRUCTURE OF THE COVALENT COMPLEX BETWEEN PORCINE PANCREATIC ELASTASE AND AC-ALA-PRO-VAL-2-BENZOXAZOLE [J].

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