ADVANTAGES TO MUTAGENESIS TECHNIQUES GENERATING POPULATIONS CONTAINING THE COMPLETE SPECTRUM OF SINGLE CODON CHANGES

被引：11

作者：

SIROTKIN, K ^{[1
]}

机构：

[1] UNIV TENNESSEE,GRAD PROGRAM CELLULAR MOLEC & DEV BIOL,KNOXVILLE,TN 37996

来源：

JOURNAL OF THEORETICAL BIOLOGY | 1986年 / 123卷 / 03期

关键词：

D O I：

10.1016/S0022-5193(86)80242-9

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：261 / 279

页数：19

共 41 条

[1] INVITRO METHYLATION OF BACTERIOPHAGE-LAMBDA DNA BY WILD-TYPE (DAM+) AND MUTANT (DAMH) FORMS OF THE PHAGE-T2 DNA ADENINE METHYLASE [J].

BROOKS, JE ;

HATTMAN, S .

JOURNAL OF MOLECULAR BIOLOGY, 1978, 126 (03) :381-394

[2] COMPARISON OF WILD-TYPE AND MUTANT RIBITOL DEHYDROGENASES FROM KLEBSIELLA-AEROGENES [J].

BURLEIGH, BD ;

RIGBY, PWJ ;

HARTLEY, BS .

BIOCHEMICAL JOURNAL, 1974, 143 (02) :341-352

[3]

CARBON J, 1977, RECOMBINANT MOL IMPA

[4] THE USE OF DOUBLE MUTANTS TO DETECT STRUCTURAL-CHANGES IN THE ACTIVE-SITE OF THE TYROSYL-TRANSFER RNA-SYNTHETASE (BACILLUS-STEAROTHERMOPHILUS) [J].

CARTER, PJ ;

WINTER, G ;

WILKINSON, AJ ;

FERSHT, AR .

CELL, 1984, 38 (03) :835-840

[5] THE CONSEQUENCES OF BASE-PAIR SUBSTITUTION MUTATIONS IN AT-RICH AND GC-RICH BACTERIA [J].

CLARKE, CH .

JOURNAL OF THEORETICAL BIOLOGY, 1983, 105 (01) :117-131

[6] THE LEEUWENHOEK LECTURE, 1979 - EXPERIMENTS IN MICROBIAL EVOLUTION - NEW ENZYMES, NEW METABOLIC-ACTIVITIES [J].

CLARKE, PH .

PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1980, 207 (1169) :385-404

[7]

Clocksin W. F., 1984, PROGRAMMING PROLOG

[8] REDESIGNING TRYPSIN - ALTERATION OF SUBSTRATE-SPECIFICITY [J].

CRAIK, CS ;

LARGMAN, C ;

FLETCHER, T ;

ROCZNIAK, S ;

BARR, PJ ;

FLETTERICK, R ;

RUTTER, WJ .

SCIENCE, 1985, 228 (4697) :291-297

[9]

Dayhoff MO, 1979, ATLAS PROTEIN SEQ S3, V5

[10]

DENG GR, 1983, METHOD ENZYMOL, V100, P96

← 1 2 3 4 5 →