MECHANISTIC STUDIES OF BIOLOGICAL GLYCOSYLATION - DETERMINATION OF THE GLUCOSYLATING REACTIVITY OF URIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE (UDPG) AND ASSESSMENT OF THE CATALYTIC POWER OF THE GLYCOSYLTRANSFERASES

被引：2

作者：

BEDFORD, CT ^{[1
]}

HICKMAN, AD ^{[1
]}

LOGAN, CJ ^{[1
]}

机构：

[1] SHELL RES LTD,SITTINGBOURNE RES CTR,SITTINGBOURNE ME9 8AG,KENT,ENGLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1992年 / 2卷 / 12期

关键词：

D O I：

10.1016/S0960-894X(00)80419-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Enzymic rate enhancements of the glycosyltransferases are estimated to be in the order of 10(10), as revealed by a determination for the first time of the magnitude of the spontaneous glucosylating reactivity (which prevails only below pH 3) of the prototypical 'activated' co-substrate of biological glycosylation, UDPG.

引用

页码：1513 / 1518

页数：6

共 9 条

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