GROWTH-RELATED PROTEINASES IN CULTURED HUMAN TUMOR-CELLS

被引：9

作者：

SCOTT, GK

TSE, CA

机构：

[1] Department of Biochemistry, University of Auckland

来源：

BIOLOGICAL CHEMISTRY HOPPE-SEYLER | 1992年 / 373卷 / 07期

关键词：

TUMOR CELLS; CELL PROLIFERATION; TUMOR PROGRESSION; PROTEINASE; PROTEINASE INHIBITOR;

D O I：

10.1515/bchm3.1992.373.2.605

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The proliferation of normal cells, and of early-passage cells from tumours, is inhibited as a consequence of inhibition of a cell-surface proteinase activity. In contrast, established tumour cell lines are usually resistant to these effects. It has previously been suggested that the change from sensitivity to resistance may be a consequence of tumour progression, but experiments with an additional three human tumour cell cultures show that this change is not inevitable.

引用

页码：605 / 609

页数：5

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