DEPOT ANTIPSYCHOTICS IN THE PROPHYLAXIS OF BIPOLAR AFFECTIVE-DISORDER

被引：49

作者：

LITTLEJOHN, R

LESLIE, F

COOKSON, J

机构：

[1] Academic Unit, Human Psychopharmacology, Royal London Hospital, London E3 4LL

来源：

BRITISH JOURNAL OF PSYCHIATRY | 1994年 / 165卷

关键词：

D O I：

10.1192/bjp.165.6.827

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Background. The efficacy of depot antipsychotic drugs in the prophylaxis of bipolar affective disorder was investigated. Method. Life charts were constructed for 18 outpatients with bipolar disorder receiving prophylactic treatment with depot medication. The durations of affective episodes were compared during periods on or off medication. Results. The subjects suffered fewer relapses and spent significantly less time in hospital (P=0.001) for treatment df manic, depressive and mixed affective illness during treatment with depot antipsychotics. Conclusions. Depot antipsychotic medication may be a useful prophylactic treatment for certain patients with bipolar affective disorder.

引用

页码：827 / 829

页数：3

共 9 条

[1] FLUPENTIXOL DECANOATE IN RECURRENT MANIC-DEPRESSIVE ILLNESS - A COMPARISON WITH LITHIUM [J].