SYNTHESIS OF 2-MODIFIED 1,3-DIACYLGLYCEROLS

被引：16

作者：

HAFTENDORN, R ^{[1
]}

ULBRICHHOFMANN, R ^{[1
]}

机构：

[1] UNIV HALLE WITTENBERG, DEPT BIOCHEM BIOTECHNOL, D-06099 HALLE, GERMANY

来源：

TETRAHEDRON | 1995年 / 51卷 / 04期

关键词：

D O I：

10.1016/0040-4020(94)01013-P

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

I,3-Diacylglycerols modified in 2-position were synthesized by combining enzymatic and chemical methods. The syntheses started from the regioisomerically pure 1,3-dilauroylglycerol or 1,3-dimyristoylglycerol obtained from glycerol and vinyl esters of carboxylic acids by means of lipase from Mucor mihei. The 2-hydroxyl group in the glycerol derivatives was subsequently substituted by phosphate as well as its disodium salt, by sulfate, phosphocholine, the benzyloxy, the succinimidyl or the amino group.

引用

页码：1177 / 1186

页数：10

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