THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS IN OBESITY

被引：44

作者：

CHALEW, S

NAGEL, H

SHORE, S

机构：

[1] Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland

来源：

OBESITY RESEARCH | 1995年 / 3卷 / 04期

关键词：

D O I：

10.1002/j.1550-8528.1995.tb00163.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The hypothalamic-pituitary-adrenal (RPA) axis normally maintains the concentration of cortisol within a narrow range with a diurnal variation characterized by higher cortisol concentrations in the morning and reduced levels in the evening, Excessive or deficient secretion of cortisol is associated with pathologic changes, Obesity has been linked with age, sex and racial alterations in the functioning of the HPA axis which are reviewed. The possible relationship of altered HPA axis activity with the long-term complications of obesity are considered.

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页码：371 / 382

页数：12

相关论文

共 136 条

[1] NALTREXONE SUPPRESSES HYPERPHAGIA INDUCED IN THE RAT BY A HIGHLY PALATABLE DIET [J].

APFELBAUM, M ;

MANDENOFF, A .

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1981, 15 (01) :89-91

[2] SERUM CORTISOL-LEVELS IN CUSHINGS-SYNDROME AFTER LOW-DOSE AND HIGH-DOSE DEXAMETHASONE SUPPRESSION [J].

ASHCRAFT, MW ;

VANHERLE, AJ ;

VENER, SL ;

GEFFNER, DL .

ANNALS OF INTERNAL MEDICINE, 1982, 97 (01) :21-26

[3] NALOXONE DECREASES FOOD-INTAKE IN OBESE HUMANS [J].

ATKINSON, RL .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1982, 55 (01) :196-198

[4] THE EFFECTS OF GLUCOSE-INGESTION AND FASTING ON PLASMA-IMMUNOREACTIVE BETA-ENDORPHIN, ADRENOCORTICOTROPIC HORMONE AND CORTISOL IN OBESE SUBJECTS [J].

BALONPERIN, S ;

KOLANOWSKI, J ;

BERBINSCHI, A ;

FRANCHIMONT, P ;

KETELSLEGERS, JM .

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1991, 14 (11) :919-925

[5] PITUITARY RESPONSE TO INSULIN-INDUCED HYPOGLYCEMIA IN OBESE SUBJECTS BEFORE AND AFTER FASTING [J].

BELL, JP ;

DONALD, RA ;

ESPINER, EA .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1970, 31 (05) :546-+

[6] IMPAIRED BETA-ENDORPHIN RESPONSE TO HUMAN CORTICOTROPIN-RELEASING HORMONE IN OBESE CHILDREN [J].

BERNASCONI, S ;

PETRAGLIA, F ;

IUGHETTI, L ;

MARCELLINI, C ;

LAMBORGHINI, A ;

FACCHINETTI, F ;

GENAZZANI, AR .

ACTA ENDOCRINOLOGICA, 1988, 119 (01) :7-10

[7] SEROTONINERGIC RECEPTOR ACTIVATION BY DEXTROFENFLURAMINE ENHANCES THE BLUNTED PITUITARY-ADRENAL RESPONSIVENESS TO CORTICOTROPIN-RELEASING HORMONE IN OBESE SUBJECTS [J].

BERNINI, GP ;

ARGENIO, GF ;

DELCORSO, C ;

VIVALDI, MS ;

BIRINDELLI, R ;

FRANCHI, F .

METABOLISM-CLINICAL AND EXPERIMENTAL, 1992, 41 (01) :17-21

[8]

BJORNTORP P, 1991, INT J OBESITY, V15, P67

[9]

BJORNTORP P, 1992, OBESITY, P579

[10] GLUCOSE-METABOLISM IN PATIENTS WITH CUSHINGS-SYNDROME [J].

BOWES, SB ;

BENN, JJ ;

SCOBIE, IN ;

UMPLEBY, AM ;

LOWY, C ;

SONKSEN, PH .

CLINICAL ENDOCRINOLOGY, 1991, 34 (04) :311-316

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