AN ANALYSIS OF THE PROCESS OF HUMAN-IMMUNODEFICIENCY-VIRUS SEXUAL RISK BEHAVIOR-CHANGE

被引:15
作者
BLOWER, SM
VANGRIENSVEN, GJP
KAPLAN, EH
机构
[1] Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco General Hospital, San Francisco, CA
[2] Department of Public Health, Municipal Health Service, Amsterdam
[3] School of Organization and Management, Yale University, New Haven, CT
关键词
HIV AIDS; RISK BEHAVIOR; MARKOV MODELS; PROCESS; PATTERN; EXPOSURE CATEGORIZATION; COHORT STUDY; DATA COLLECTION;
D O I
10.1097/00001648-199505000-00008
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Few studies have tried to identify the process of risk behavior change. In this paper, we present a method for the analysis of the process of risk behavior change; the methodology involves using time series data to form transition probability matrices. We apply the method to human immunodeficiency virus (HIV) sexual risk behavioral data from a cohort of gay men in Amsterdam. We determine the process of risk behavior change in this cohort, and we demonstrate that it is not possible to deduce the process simply from an examination of the static pattern. Our results imply that the risk behavior change that is observed in this cohort may be viewed as a homogeneous one-step Markovian process. This process of risk behavior change has implications for the long-term prediction of HIV seroconversion rates and for the design and evaluation of HIV behavioral intervention studies and vaccine trials. Our results also have implications for the interpretation of relapse behavior.
引用
收藏
页码:238 / 242
页数:5
相关论文
共 20 条
[1]  
Trichopoulos D., Sparos L., Petridou E., Homosexual role separation and the spread of AIDS, Lancet, 2, (1988)
[2]  
van Griensven G.J.P., de Vroome E.M.M., Veugelers P.J., Coutinho R.A., Heterogeneity and Fluctuations in Homosexual Role Behaviour: Implications for Modelling the AIDS Epidemic, (1990)
[3]  
van Zessen G.J.P., van Griensven G., Heterogeneous mixing models, homosexual role separation and consistency over time, AIDS Impact Assessment Modelling and Scenario Analysis, (1992)
[4]  
Coxon A.P.M., Coxon N.H., Weatherburn P., Hunt A.J., Hickson F., Davies P.M., McManus T.J., Sex role separation and sexual diaries of homosexual men, AIDS, 7, pp. 877-882, (1993)
[5]  
Lzazola J.A., Valdespino-Gomez J.L., Gortmaker S.L., Townsend J., Becker J., Palacios-Martinez M., Mueller N.E., Amor J.S., HIV-1 seropositivity and behavioral and sociological risks among homosexual and bisexual men in six Mexican cities, J Acquit Immune Defic Syndr, 4, pp. 614-622, (1991)
[6]  
Kingsley L.A., Detels R., Kaslow R., Polk B.F., Charles R.R., Chmiel J., Detre K., Kelsey S.F., Odaka N., Ostrow D., van Raden M., Visscher B., Risk factors for seroconversion to human immunodeficiency virus among male homosexuals: Results from the multicenter AIDS cohort study, Lancet, 1, pp. 345-348, (1987)
[7]  
Winkelstein W., Lyman D.M., Padian N., Grant R., Samuel M., Wiley J.A., Anderson R.E., Lang W., Riggs J., Levy J.A., Sexual practices and risk of infection by the human immunodeficiency virus, JAMA, 257, pp. 321-325, (1987)
[8]  
Stevens C.E., Taylor P.E., Zang E.A., Morrison J.M., Harley E.J., de Cordoba S.R., Bacino C., Ting C.Y., Bodner A.J., Sarngadharan M.G., Gallo R.C., Rubinstein P., Human T cell lymphotropic virus type III infection in a cohort of homosexual men in NYC, JAMA, 255, pp. 2167-2172, (1986)
[9]  
van Griensven G.J.P., Tielman R.A.P., Goudsmit J., van der Noordaa J., de Wolf F., de Vroome E.M.M., Coutinho R.A., Risk factors and prevalence of HIV antibodies among homosexual men in the Netherlands, Am J Epidemiol, 125, pp. 1048-1057, (1987)
[10]  
Hernandez M., Uribe M.P., Gortmaker S., Avila C., de Caso E., Mueller N., Sepulveda J., Sexual behaviour and status for human immunodeficiency virus type I among homosexual and bisexual males in Mexico City, Am J Epidemiol, 135, pp. 883-894, (1992)