FORMATION OF THE LIGNAN, (-)SECOISOLARICIRESINOL, BY CELL-FREE-EXTRACTS OF FORSYTHIA-INTERMEDIA

被引：43

作者：

UMEZAWA, T ^{[1
]}

DAVIN, LB ^{[1
]}

LEWIS, NG ^{[1
]}

机构：

[1] VIRGINIA POLYTECH INST & STATE UNIV,DEPT BIOCHEM,COMMONWEALTH CTR WOOD & SCI TECHNOL,BLACKSBURG,VA 24061

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1990年 / 171卷 / 03期

关键词：

D O I：

10.1016/0006-291X(90)90784-K

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A crude cell-free extract from Forsythia intermedia catalyses the formation of (-)secoisolariciresinol, and not its (+) enantiomer, when incubated with coniferyl alcohol in the presence of NAD(P)H and H2O2. This is the first report of an enzyme reaction specifically involved in the coupling reaction between two phenylpropanoid monomers to afford an optically pure lignan. © 1990.

引用

页码：1008 / 1014

页数：7

共 10 条

[1] SESAMIN FROM BARK OF 2-AFRICAN ZANTHOXYLUM SPECIES [J].

FISH, F ;

WATERMAN, PG ;

FINKELSTEIN, N .

PHYTOCHEMISTRY, 1973, 12 (10) :2553-2554

[2]

FREUDENBERG K, 1965, SCIENCE, V148, P195

[3]

GOODWIN TW, 1983, INTRO PLANT BIOCH, P559

[4]

KARU T, 1937, J PHARM SOC JAPAN, V57, P184

[5] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF E-MONOLIGNOLS AND Z-MONOLIGNOLS AND THEIR GLUCOSIDES [J].

LEWIS, NG ;

INCIONG, MEJ ;

DHARA, KP ;

YAMAMOTO, E .

JOURNAL OF CHROMATOGRAPHY, 1989, 479 (02) :345-352

[6] BIOSYNTHESIS OF LIGNANS IN FORSYTHIA-INTERMEDIA [J].

RAHMAN, MMA ;

DEWICK, PM ;

JACKSON, DE ;

LUCAS, JA .

PHYTOCHEMISTRY, 1990, 29 (06) :1841-1846

[7]

Rao C B S, 1978, CHEM LIGNANS

[8]

UMEZAWA T, 1990, J C S CHEM COMMUN

[9]

UMEZAWA T, UNPUB J BIOL CHEM

[10]

1979, BIORAD PROTEIN ASSAY

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