CHRONIC HYPERTROPHIC CRANIAL PACHYMENINGITIS ASSOCIATED WITH HTLV-1 INFECTION

被引：40

作者：

KAWANO, Y ^{[1
]}

KIRA, J ^{[1
]}

机构：

[1] KYUSHU UNIV,FAC MED,INST NEUROL,DEPT NEUROL,FUKUOKA 812,JAPAN

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1995年 / 59卷 / 04期

关键词：

HYPERTROPHIC CRANIAL PACHYMENINGITIS; HTLV-I INFECTION;

D O I：

10.1136/jnnp.59.4.435

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Two patients presenting with recurrent multiple cranial neuropathy showed diffuse thickening and gadolinium enhancement of the dura mater on brain MRI. Both had anti-HTLV-I antibodies in serum. A quantitative polymerase chain reaction study of the peripheral blood disclosed that the HTLV-I proviral DNA loads increased considerably in one case and moderately in the other. Both showed a spontaneous proliferation of peripheral blood lymphocytes as well as an increase in helper/inducer T cells. Neither had any other underlying infections or autoimmune diseases. Thus it is possible that hypertrophic pachymeningitis developed as a result of multiorgan involvement of HTLV-I infection in these patients.

引用

页码：435 / 437

页数：3

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