COMPARISON OF SUPEROXIDE WITH OTHER REDUCING AGENTS IN THE BIOLOGICAL PRODUCTION OF HYDROXYL RADICALS

被引：264

作者：

WINTERBOURN, CC

机构：

来源：

BIOCHEMICAL JOURNAL | 1979年 / 182卷 / 02期

关键词：

D O I：

10.1042/bj1820625

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Iron--EDTA was shown to catalyse OH. production from H2O2 and ascorbate by a mechanism largely independent of superoxide. When ascorbate and superoxide were both present, the ascorbate mechanism was more important than superoxide as a source of OH., and would appear to be more significantly biologically.

引用

页码：625 / 628

页数：4

共 15 条

[1] BIOLOGICAL DEFENSE MECHANISMS - PRODUCTION BY LEUKOCYTES OF SUPEROXIDE A POTENTIAL BACTERICIDAL AGENT [J].