RESPIRABLE PARTICULATES GENERATED BY PRESSURIZED CONSUMER PRODUCTS .2. INFLUENCE OF EXPERIMENTAL CONDITIONS

The simulated breathing zone approach has been used to study aerosols generated by pressurized consumer products. The model has been applied to the characterization of several products under one set of conditions and to the determination of the influence product discharge conditions have on the characteristics of the particulates to which a user might be exposed. The relative insensitivity of the particulate size characteristics to the experimental variations suggests that the fractions of the aerosol in the simulated breathing zone falling into each size range shown in Table II of our previous paper1)can be used in estimating human exposure. The concentration values presented in that paper, however, are subject to variation depending on use conditions. Those data represent a measurement of concentration in the simulated breathing zone that is greater than any likely to be encounter under actual use conditions. Thus, in the absence of extensive, reliable data describing the distribution of exposures under actual use conditions, the values presented in the previous paper are a useful, conservative estimate of the exposure of users of pressurized products and can serve as the basis for designing inhalation toxicologic studies on pressurized products or ingredients in these products. Copyright 1979, American Industrial Hygiene Association