STOICHIOMETRIC MONO N-FUNCTIONALIZATION OF TETRAAZAMACROCYCLES VIA PHOSPHORYL-PROTECTED INTERMEDIATES

被引：72

作者：

FILALI, A

YAOUANC, JJ

HANDEL, H

机构：

[1] Unité de Recherche, Associée Au Cnrs N°322 Chimie, Facultè Des Sciences Et Techniques, Brest, F‐29287, 6, avenue le Gorgeu

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1991年 / 30卷 / 05期

关键词：

D O I：

10.1002/anie.199105601

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The selective alkylation of one N atom of tetraaza macrocycles (1) occurs simply and in high yields according to the reaction sequence shown below. Compounds 2 and 3 can be regarded as cyclic analogues of hexamethylphosphoramide; they contain one reactive N atom in addition to three ''inert'' N atoms.

引用

页码：560 / 561

页数：2

共 9 条

[1] ATKINS TJ, 1978, TETRAHEDRON LETT, V52, P5149
[2] IMPROVED SYNTHESIS OF CYCLAMPHOSPHINE OXIDE, A POTENTIAL BIDENTATE ASYMMETRIC LIGAND - SYNTHESIS AND CHARACTERIZATION OF SOME OF ITS RHODIUM COMPLEXES - MOLECULAR AND CRYSTAL-STRUCTURE OF (CYCLAMPHOSPHINE OXIDE)DICARBONYLCHLORORHODIUM(I)
BOUVIER, F
DUPART, JM
GRAND, A
RIESS, JG
[J]. INORGANIC CHEMISTRY, 1987, 26 (13) : 2090 - 2093
[3] COORDINATION CHEMISTRY OF CYCLAMPHOSPHORANE - ACCESS TO TRANSITION-METAL CYCLAMPHOSPHORANIDES - CRYSTAL AND MOLECULAR-STRUCTURE OF CPMO(CO)2(CYCLAMPHOSPHORANIDE)
DUPART, JM
GRAND, A
RIESS, JG
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (06) : 1167 - 1173
[4] HANDEL H, 1988, Patent No. 884008392
[5] GENERAL ROUTES FOR THE SYNTHESIS OF MONO, DI AND TRI-N-SUBSTITUTED DERIVATIVES OF CYCLAM
HELPS, IM
PARKER, D
MORPHY, JR
CHAPMAN, J
[J]. TETRAHEDRON, 1989, 45 (01) : 219 - 226
[6] KADEN TA, 1984, HOST GUEST COMPLEX C, V3, P157
[7] PREPARATION OF TRIAZA-CROWN, TETRAAZA-CROWN AND PERAZA-CROWN COMPOUNDS CONTAINING AMINOALKYL SIDE GROUPS OR UNSUBSTITUTED RING NITROGEN-ATOMS
KRAKOWIAK, KE
BRADSHAW, JS
IZATT, RM
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (10) : 3364 - 3368
[8] CYCLENPHOSPHINE OXIDE - ANOMALOUS MEMBER OF A HOMOLOGOUS SERIES
RICHMAN, JE
KUBALE, JJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (04) : 749 - 751
[9] RICHMAN JE, 1981, ACS SYM SER, V171, P271

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