ENANTIOSELECTIVITY IN A FREE-RADICAL OXIDATION - MEASUREMENT OF SMALL ENANTIOMERIC EXCESSES

被引：11

作者：

BROOKS, DJ

PERKINS, MJ

SMITH, SL

GOODALL, DM

LLOYD, DK

机构：

[1] UNIV LONDON ROYAL HOLLOWAY & BEDFORD NEW COLL,DEPT CHEM,EGHAM TW20 0EX,SURREY,ENGLAND

[2] UNIV YORK,DEPT CHEM,YORK YO1 5DD,N YORKSHIRE,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2 | 1992年 / 03期

关键词：

D O I：

10.1039/p29920000393

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Partial conversion of 2-methyl-1-phenylpropan-1-ol into isobutyrophenone by the acyl aminoxyl radicals formed on oxidation of enantiomerically pure N-fenchelylbenzohydroxamic acid or its paranitro derivative occurs with small but measurable enantioselectivity. This has been demonstrated using HPLC with diode-laser-based polarimetric detection to examine unchanged alcohol in the reaction mixtures.

引用

页码：393 / 396

页数：4

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