INVITRO DEGRADATION OF A POLYHYDROXYBUTYRATE POLYHYDROXYVALERATE COPOLYMER

被引：23

作者：

KNOWLES, JC ^{[1
]}

HASTINGS, GW ^{[1
]}

机构：

[1] QUEEN MARY & WESTFIELD COLL,DEPT MAT,LONDON E1 4NS,ENGLAND

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 1992年 / 3卷 / 05期

关键词：

D O I：

10.1007/BF00705367

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Injection-moulded PHB/7% PHV (molecular mass 580 000) samples were placed in buffered saline at varying pHs for long-term in vitro studies. Anomalies between sample mass loss and Young's modulus were found for the different pHs. The Young's modulus anomaly was explained by examination of the molecular mass distribution (MMD) changes with time. The molecular mass measurements also showed that the MMD moved to a lower molecular mass, and also showed an increase in peak height, irrespective of pH. From the Mn data, curves for (Mn(0)/Mn(t)-1 ) were plotted and the linearity showed that the solution pH was a rate-controlling factor.

引用

页码：352 / 358

页数：7

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