A PROVISIONAL MECHANISM FOR REGULATING THE AMINOACYL-TRANSFER RNA-SYNTHETASES

被引:3
作者
BLACK, S
机构
[1] Laboratory of Biochemical Pharmacology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda
关键词
D O I
10.1006/bbrc.1993.1189
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A mechanism is outlined for regulating aminoacyl-tRNA synthetases with a nonheme iron-containing protein serving as the key regulator. This mechanism is formulated from experiments with a complex-bound valyl-tRNA synthetase from yeast that is activated by thiols, by tRNA, and by an iron-containing protein preparation with characteristic spectral properties. © 1993 Academic Press, Inc.
引用
收藏
页码:95 / 102
页数:8
相关论文
共 19 条
[1]  
BERG P, 1961, J BIOL CHEM, V236, P1726
[2]  
BLACK S, 1985, J BIOL CHEM, V260, P433
[4]  
BLACK S, 1983, J BIOL CHEM, V258, P2112
[5]  
BLACK S, 1969, J BIOL CHEM, V244, P1656
[6]   EVIDENCE FOR A NEW ENZYME CONNECTED WITH PROTEIN SYNTHESIS [J].
BOMAN, HG ;
SVENSSON, I .
NATURE, 1961, 191 (478) :674-&
[7]  
BUCHANAN BB, 1970, ADV ENZYMOL REL S BI, V33, P119
[8]   REGULATION OF CO2 ASSIMILATION IN OXYGENIC PHOTOSYNTHESIS - THE FERREDOXIN THIOREDOXIN SYSTEM - PERSPECTIVE ON ITS DISCOVERY, PRESENT STATUS, AND FUTURE-DEVELOPMENT [J].
BUCHANAN, BB .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1991, 288 (01) :1-9
[9]   A MODIFIED FERROZINE METHOD FOR THE MEASUREMENT OF ENZYME-BOUND IRON [J].
DAVIS, MD ;
KAUFMAN, S ;
MILSTIEN, S .
JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS, 1986, 13 (01) :39-45
[10]   AMINOACYL TRANSFER RNA-SYNTHETASE STIMULATORY FACTORS AND INORGANIC PYROPHOSPHATASE [J].
DIGNAM, JD ;
DEUTSCHER, MP .
BIOCHEMISTRY, 1979, 18 (14) :3165-3170