INTERFERON INDUCTION IN MURINE PERITONEAL MACROPHAGE BY STIMULATION WITH LACTOBACILLUS-ACIDOPHILUS

被引:35
作者
KITAZAWA, H [1 ]
MATSUMURA, K [1 ]
ITOH, T [1 ]
YAMAGUCHI, T [1 ]
机构
[1] TOHOKU UNIV,FAC AGR,DEPT ANIM SCI,ANIM MORPHOL LAB,SENDAI,MIYAGI 981,JAPAN
关键词
D O I
10.1111/j.1348-0421.1992.tb01668.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Induction of interferon for a kind of dairy lactic acid bacteria, Lactobacillus acidophilus (L. acidophilus), was investigated in murine peritoneal macrophage (M-phi) cultures. Lactobacillus acidophilus JCM 1034, 1132T, 1229 and 2125 induced IFN (12-34 I.U./ml) in M-phi cultures in vitro. Strain 1132T- and 2125-induced IFNs were characterized as IFN-alpha/beta by treatment with anti-IFNs serum. The results indicate that the inducing activity of IFNs may be one of the available biological parameters for designating the dairy products containing L. acidophilus as "physiologically functional foods."
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页码:311 / 315
页数:5
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