SENSITIVITY OF MEASLES-VIRUS HEMOLYSIN TO ACETONE AND THE PREPARATION OF MONOSPECIFIC HUMAN ANTI-HAEMOLYSIN BY ABSORPTION

被引:10
作者
ARMSTRONG, MA [1 ]
FRASER, KB [1 ]
SHIRODARIA, PV [1 ]
机构
[1] QUEENS UNIV BELFAST, DEPT MICROBIOL & IMMUNOL, BELFAST BT12 6BN, ANTRIM, NORTH IRELAND
关键词
D O I
10.1099/0022-1317-44-2-541
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The hemolysin of measles virus, either in the virion or in infected cells [African green monkey kidney], is functionally and antigenically sensitive to acetone. Absorption of human sera with acetone-treated, measles virus-infected cells removes antibodies to all measles virus structural antigens except hemolysin. The antibody titers of absorbed sera give good correlation in HLI [hemolysin-inhibiting antibodies], neutralization and fluorescent antibody staining on unfixed infected cells.
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页码:541 / 544
页数:4
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