TESTING MODELS FOR GENETIC DETERMINATION IN MIGRAINE

被引：66

作者：

MOCHI, M ^{[1
]}

SANGIORGI, S ^{[1
]}

CORTELLI, P ^{[1
]}

CARELLI, V ^{[1
]}

SCAPOLI, C ^{[1
]}

CRISCI, M ^{[1
]}

MONARI, L ^{[1
]}

PIERANGELI, G ^{[1
]}

MONTAGNA, P ^{[1
]}

机构：

[1] UNIV FERRARA,DIPARTIMENTO BIOL EVOLUT,FERRARA,ITALY

来源：

CEPHALALGIA | 1993年 / 13卷 / 06期

关键词：

D O I：

10.1046/j.1468-2982.1993.1306389.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We collected two clinically matched samples of patients, one sample affected by migraine with aura the other by migraine without aura, to investigate the genetic determination of these conditions. A maternal and X-linked transmission for both these diseases was considered unlikely after pedigree analysis. Classical segregation analysis indicated a likely autosomal recessive kind of transmission for both. Reduced penetrance and the h(2) values, however, imply the presence of additional genetic and/or environmental factors controlling the phenotypic expression of migraine.

引用

页码：389 / 394

页数：6

共 16 条

[1] GENETICS OF MIGRAINE AND MIGRAINE ACCOMPAGNEE - A STUDY OF 81 CHILDREN AND THEIR FAMILIES [J].