TRANSIENT CO2 ELIMINATION AND STORAGE AS FUNCTIONS OF THE VENTILATORY RESPONSE TO CO2

被引：4

作者：

DAMOKOSHGIORDANO, A ^{[1
]}

LONGOBARDO, GS ^{[1
]}

CHERNIACK, NS ^{[1
]}

机构：

[1] HOSP UNIV PENN, DEPT MED, DIV CARDIOVASC PULM, PHILADELPHIA, PA 19104 USA

来源：

RESPIRATION PHYSIOLOGY | 1979年 / 37卷 / 03期

关键词：

Chemoreceptors; CO[!sub]2[!/sub] elimination; CO[!sub]2[!/sub] storage; Control of breathing; Ventilatory response to CO[!sub]2[!/sub; Ventilatory threshold to CO[!sub]2[!/sub;

D O I：

10.1016/0034-5687(79)90072-0

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The effect on CO2 storage and elimination of variations in the slope and intercept of the ventilatory response to CO2 curve was examined. Theoretical and experimental results show that although CO2 elimination rate following a transient ventilatory disturbance in decreased at low ventilatory response slopes, this decrease can be compensated by elevated PCO intercepts, or thresholds. Conversely, high CO2 elimination rate following a ventilatory disturbance due to a high ventilatory response slope can be off-set by a depressed PCO threshold. The results suggest that elevated thresholds which often accompany depressed ventilatory response slopes may be part of a compensatory mechanism for minimizing transient hypercapnia and acidosis. © 1978.

引用

页码：219 / 237

页数：19

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