FURTHER STUDIES ON INHIBITION OF MONOAMINE OXIDASE BY M + B 9302 (CLORGYLINE) .2. COMPARISON OF M + B 9302 INHIBITION WITH THAT OF IPRONIAZID

The mode of action of two monoamine oxidase (MAO) inhibitors, M & B 9302, N-methyl-N-propargyl-3(2,4-dichlorophenoxy)propylamine hydrochloride, and iproniazid (N-isonicotinyl-N'-isopropylhydrazine), is compared. Unlike inhibition by iproniazid, there was no lag phase before the onset of inhibition by M & B 9302 nor was the inhibition affected by cyanide or copper ions. © 1969.