EFFECTS OF COLD OR RESTRAINT ON INCIDENCE OF GASTRIC ULCERATION INDUCED IN RATS BY ULCEROGENIC DRUGS

被引：5

作者：

DJAHANGUIRI, B

ZARRINDAST, MR

GERAYESHNEJAD, S

机构：

[1] Department of Pharmacology, School of Medicine, Tehran University, Tehran

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1978年 / 51卷 / 01期

关键词：

Aspirin; Cimetidine; Cold; Histamine; Indomethacin; Phenylbutazone; Restraint; Stomach;

D O I：

10.1016/0014-2999(78)90064-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Exposure to cold (4°C) or restraint increased the incidence and severity of gastric ulceration induced after i.p. injection of phenylbutazone, aspirin and indomethacin but not of histamine. Oral administration of cimetidine, an H2-receptor blocker, 30 min before drug injection, prevented the occurence of gastric lesions. © 1978.

引用

页码：77 / 79

页数：3

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