INTRAVENOUS IMMUNOGLOBULIN TREATMENT OF WOMEN WITH MULTIPLE MISCARRIAGES

被引：45

作者：

CHRISTIANSEN, OB

MATHIESEN, O

LAURITSEN, JG

GRUNNET, N

机构：

[1] Department of Clinical Immunology, Aalborg Hospital, DK 9100, Aalborg

[2] Department of Obstetrics and Gynaecology, Aalborg Hospital, DK 9100, Aalborg

来源：

HUMAN REPRODUCTION | 1992年 / 7卷 / 05期

关键词：

ABORTION; IMMUNOGLOBULIN; RECURRENT ABORTION;

D O I：

10.1093/oxfordjournals.humrep.a137724

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Eleven women who had previously experienced four to eight unexplained fetal losses (median 6.0 fetal losses/woman) were treated in their next pregnancy with individualized doses of pooled intravenous immunoglobulins. Nine women (82%) delivered healthy infants subsequent to the treatment. Prior to treatment, the pregnant patients had a significantly (P < 0.05) increased median level of complement C3 neodeterminants in the blood compared with a group of 33 normal first trimester pregnant women. This may be a sign of increased turnover of complement in these women.

引用

页码：718 / 722

页数：5

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