OVERGROWTH AND PRUNING OF DENDRITES IN ADULT-RATS RECOVERING FROM NEOCORTICAL DAMAGE

被引：275

作者：

JONES, TA

SCHALLERT, T

机构：

[1] UNIV TEXAS,DEPT PSYCHOL,AUSTIN,TX 78712

[2] UNIV TEXAS,INST NEUROSCI,AUSTIN,TX 78712

来源：

BRAIN RESEARCH | 1992年 / 581卷 / 01期

关键词：

PLASTICITY; DENDRITIC BRANCHING; RECOVERY OF FUNCTION; MOTOR CORTEX; FORELIMB PREFERENCE; GOLGI-COX; PYRAMIDAL NEURON;

D O I：

10.1016/0006-8993(92)90356-E

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Unilateral lesions to the forelimb representation (FL) area of the rat sensorimotor cortex caused a time-dependent increase in the dendritic arborization of layer V pyramidal neurons in the contralateral homotopic cortex. The increase in arborization was maximum at 2-3 weeks after the lesion, following which there was a partial reduction in dendritic branching. These neural morphological changes may be related to post-lesion behavioral changes in the use of the forelimbs.

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页码：156 / 160

页数：5

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