EFFECT OF DIPYRIDAMOLE ON THE SURVIVAL OF EXPERIMENTAL CRITICAL SKIN FLAPS

被引：8

作者：

ARNANDER, C

JURELL, G

TORNLING, G

UNGE, G

机构：

[1] KAROLINSKA HOSP, DEPT PATHOL, S-10401 STOCKHOLM, SWEDEN

[2] KAROLINSKA HOSP, DEPT PLAST SURG, S-10401 STOCKHOLM, SWEDEN

[3] KAROLINSKA HOSP, DEPT THORAC MED, S-10401 STOCKHOLM, SWEDEN

来源：

SCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY AND HAND SURGERY | 1979年 / 13卷 / 02期

关键词：

D O I：

10.3109/02844317909013067

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The effect of dipyridamole (Persantin) on the survival of experimental skin flaps was studied [in rats]. In controls 39% of the skin flap area survived. I.p. injection of dipyridamole 4 mg/kg twice daily starting 4 h preoperatively increased the surviving area by 18%. This increase is statistically significant (P < 0.05). The improved survival could be due to the vasodilatory action of the drug and/or proliferation of small blood vessels induced by the drug.

引用

页码：261 / 262

页数：2

共 8 条

[1]

BUCHNER T, 1968, ARZNEI-FORSCHUNG, V18, P170

[2] ANTILIPOLYTIC EFFECT OF ADENOSINE IN DOG ADIPOSE-TISSUE INSITU [J].

FREDHOLM, BB ;

SOLLEVI, A .

ACTA PHYSIOLOGICA SCANDINAVICA, 1977, 99 (02) :254-256

[3]

HAUSS WH, 1976, ARZNEIMITTEL-FORSCH, V17, P964

[4]

Junge-Hulsing G, 1967, Med Welt, V49, P2961

[5] INCREASED SURVIVAL OF EXPERIMENTAL SKIN FLAPS IN RATS FOLLOWING TREATMENT WITH ANTI-ADRENERGIC DRUGS [J].

JURELL, G ;

JONSSON, CE .

SCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY AND HAND SURGERY, 1976, 10 (03) :169-172

[6]

KADATZ R, 1973, HERZ KREISLAUF, V5, P519

[7] IMPROVEMENT OF BLOOD CIRCULATION IN EXPERIMENTAL SKIN FLAPS BY PHENTOLAMINE [J].

NORBERG, KA ;

PALMER, B .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1969, 8 (01) :36-&

[8] UPTAKE AND METABOLISM OF ADENOSINE BY HUMAN ERYTHROCYTE GHOSTS [J].

SCHRADER, J ;

RUBIO, R ;

BERNE, RM .

AMERICAN JOURNAL OF PHYSIOLOGY, 1972, 223 (01) :159-&

← 1 →